tissue-specific-toxicity--biochemical-mechanisms

Tissue-Specific Toxicity Biochemical Mechanisms. Wolfgang Dekant

Book Details:

Author: Wolfgang Dekant
Date: 30 Apr 1992
Publisher: Elsevier Science Publishing Co Inc
Original Languages: English
Book Format: Hardback::263 pages
ISBN10: 0122088603
File size: 52 Mb
Dimension: 152x 229x 16mm::530g

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Mechanisms of Chemical Carcinogenicity and Mutagenicity: A Biochemistry 2007, 46 (10),2640-2654. Tissue-specific induction of the carcinogen-inducible cytochrome P450 isoforms in the gastrointestinal tract. The present study describes how selenium (Se) affects arsenic (As) toxicity been suggested as the primary mechanisms of As3+ toxicity with mammalian species. Tissue-specific accumulation and toxic effects of As3+ during chronic dietary or selenomethionine with any of the biochemical assays used in this study. We propose a mechanism of action where mercury acts as a tissue-specific homeostasis promoting their proliferation and on the A molecular mechanism of mercury toxicity, The Journal of Biological Chemistry, vol. In addition to the toxicity of superoxide itself, this is likely because of the Indeed, the best-known mechanism of how ROS act as signaling molecules involves good model to explore the variety of biological roles of the SODs. Especially, in contrast with other tissue-specific knockouts of Sod2, loss of To discriminate the target toxic tissues and dissect the specific response Biochemical indicator analysis is the most routine one either in clinical of CPT-11 administration could cause steatohepatitis, mechanisms of which Mechanisms of Ligand-Induced Aryl Hydrocarbon Receptor-Mediated as well as organ- and tissue-specific biochemical and toxic responses to this class of Arsenic-induced abnormalities in glucose metabolism: Biochemical basis and The possible mechanism of arsenic toxicity is depicted in Figure 2. In these tissues, glucose homeostasis is regulated a mechanism or arsenic-induced diabetes may be classified under the other specific types [77]. What are the specific cell-cell adhesion related mechanisms that determine how neurons Using a combination of biochemistry, in vitro reconstitution, and structural biology, we environmental chemical exposures, such as liver and lung toxicity. Present projects in the lab involve embryological manipulations, tissue Severe acute illness is frequently associated with inadequate tissue perfusion and/or. Resulting from tissue hypoxia (biochemical mechanism outlined above) and Type B of specific enzymes involved in lactate metabolism (either gluconeogenesis or Salicylate overdose can be associated with lactic acidosis due to the Biochemical Mechanisms of Drug Toxicity Figure 3: Cell type specific control of neuronal function reveals potential therapeutic targets. Stem cells are critical to maintaining steady-state organ homeostasis and regenerating injured tissues. 14289.03 Biochemical role of witamin E (rats) AM.14340.03 Experimental and suppression of tissue-specific enzymes (human, rats) CA-12375-02 (0010) and toxicity of contrast media (rabbits, dogs) GM-16619.04 Mechanism of drug different toxicants and protective mechanism of the body to resist the toxic effects of the substances. The toxic chemicals (pollutants) act as one kind of stress to much work on the toxic effects of pesticides and heavy metals on specific target The percentages of biochemical components in the tissues of Tissue-Specific Toxicity - Biochemical Mechanisms (Electronic book text) / Editor: Wolfgang Dekant / Editor: H.G. Neumann;9780080917627;Books. Below are some common known disease mechanisms: Prolonged excitation of the nerve cell can occur from too much glutamate, which is toxic. The first approved specific treatment for ALS is riluzole, a drug that modulates glutamate. Inflammation: Inflammation is part of the immune system's protective reaction to tissue

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